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In rectal cancer chemoradiotherapy and metastatic renal cell carcinoma combinations, CRLX101 has produced signals consistent with vascular normalization and radiosensitization, although randomized trials have so far shown mixed results for hard outcomes such as progression-free survival [91, 92]

The dichotomy between necrosis in the ischemic core and apoptosis in the ischemic penumbra is not strict as apoptotic death has been also shown in the ischemic core and vice versa (Ontniente et al., 2003)

Iron accumulates in Huntington's disease neurons: protection by deferoxamine

Beyond semen analysis: additional tests If your semen analysis confirms oligospermia, your doctor may recommend further investigations to pinpoint the underlying cause: Hormone panel

When intracellular oxygen availability is reduced (hypoxia), protein folding will be disturbed, leading to accumulation of misfolded or unfolded proteins