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Fukuyama congenital muscular dystrophy: clinical aspects in Translational Research in Muscular Dystrophy (eds Takeda, S., Miyagoe-Suzuki, Y

The study confirmed that FOXO4-DRI disrupts FOXO4-p53 binding in endothelial cells, facilitating phosphorylated p53 nuclear exclusion and triggering the BAX/caspase-3 apoptotic cascade specifically in senescent endothelial cells