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It cannot be ruled out that -glutamylcysteine could also act as a cofactor for other isoforms of the glutathione peroxidase family

Future studies should extend the age range or utilize meta-analysis to integrate multiple studies to investigate how brain GSH levels vary over the lifespan

doi: 10.1038/nrendo.2016.136 [DOI] [PubMed] [Google Scholar] 31

Fuzheng Quxie Decoction reduced A and tau hyperphosphorylation, improved angiogenesis and cerebral blood flow, improving learning and memory in SAMP8 mice

Loss of BBB integrity in prodromal or early symptomatic phases may exacerbate neuroinflammation and accelerate neuronal loss [201]