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These experiments confirmed that ferroptosis was the mechanism of cell death induced by the addition of GPX4 inhibition to palbociclib, which resulted in greater cell death than the single treatments

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While other PD-associate genes, such as LRRK2 , SNCA , and GBA1 , regulate lysosomal functions, lipid metabolism, or protein aggregation, some have been shown to indirectly affect the electron transport chain

Int J Vet Sci Med 6(2):286295