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By pumping the accumulated, unbound cytosolic catecholamines backward across the plasma membrane and safely into the extracellular synaptic space, the neuron is able to maintain its free cytoplasmic neurotransmitter levels below toxic thresholds , directly protecting itself from oxidative cell death and preserving neuronal viability (Underhill et al., 2021)

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The final library was sequenced on Illumina MiSeq with a v3 reagent kit (600 cycles)

Check the reconstituting tirzepatide chart for detailed volume calculations