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For behavioural analysis, animals were treated until the day before behavioural testing that was performed at 1213 wk of age

Clin Endocrinol 37(5):387397 Darcy J, Bartke A (2017) Functionally enhanced brown adipose tissue in Ames dwarf mice

Genera Fifty-nine bacterial genera were definitively identified in the cecal samples

Treatment of Drosophila flies with kynurenine pathway inhibitors and the NAD + precursors NR or NAM increased the lifespan of these animals, suggesting an advantage in combining different therapeutic strategies

Additionally, an equal amount of neutral commercial cream or saline was topically and intraperitoneally administered to the test subjects in order to act as a vehicle-control [1]