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Molina JD, Avila S, Rubio G, Lpez-Muoz F

Mediates Necroptosis by Inducing Reactive Oxygen Species Production in Bladder Cancer In Vitro

For some mutations (in total 25, distributed over the whole ligand binding domain) either a complete (CAIS) as well as a partial (PAIS) phenotype (13 cases) or a CAIS and a PAIS and a mild (MAIS) phenotype (4 cases) or a PAIS and a MAIS phenotype (8 cases) has been described, indicating that phenotype does not always match with genotype