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The inhibitory effect of GPNA on ASCT2 plays a certain role in the treatment of lung [177], pancreatic [178], and breast [179] cancers

Jiangxi J Tradit Chin Med 2022;53:124

Moreover, the proteolytic activity of the proteasome requires catalysis by the intact sulfhydryl groups of Cys residues in the subunit of the 20S core, which is susceptible to oxidative stress [26]