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doi: 10.1152/ajpregu.00428.2006 110 AfonsoRALauttWWSchaferJLegareDJOliveiraAGMacedoMP

Front Psychiatry (2018) 9:559

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In astrocytes, glutamine (Gln), the major precursor of Glu, is synthesized via Gln synthetase and transferred to neurons, where it is converted back into Glu by phosphate-activated glutaminase, further entering mitochondrial pathways