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The daily trends for a 55 years old man and woman, waking up at 7 am, are shown in Fig

10.1093/cvr/cvt205 75

doi: 10.1038/ng909

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343 According to a 2020 systematic review and meta-analysis that included 60 randomized controlled trials with a total of 4,129 patients, omega-3 fatty acid supplementation appeared to decrease the incidence of cardiovascular death by 55% in CKD patients on hemodialysis, though it did not appear to reduce mortality overall