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J., Paushkin, S., Dreyfuss, G

Alcohol treatment results in massive ROS accumulation and lipid peroxidation both in cell culture and in mouse models of ALD, which could be rescued by a ferroptosis inhibitor [74]

Founder & Prescribing Physician M.J

For the short-term experiments, the classical oxidants diamide, H 2 O 2 , 3-morpholinosydnonimine hydrochloride, the reducing agent DTT, and antimalarial drugs (Table S1) were added to trophozoite stage parasites (2630 h post invasion) of the 3D7 and Dd2 strains expressing hGrx1-roGFP2 and monitored for 4 or 9 min after 1 min of basal measurements with imaging every 10 or 20 s, respectively

Elucidating cuproptosis-associated genes in the progression from nash to HCC using bulk and single-cell RNA sequencing analyses and experimental validation