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Hydrogels are often not strong enough and are prone to deformation, making it difficult to support weight-bearing joints such as the knee, so finding the optimal polymer concentration to achieve optimal biomechanical loading is a prerequisite

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SPTs are commonly used as the initial diagnostic tool to assess sensitization by applying shellfish extract to the skin and monitoring for allergic reactions

Funding This work was financially supported by Iran University of Medical Sciences (Grant Number: 1402-2-75-25008)