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An ACO's historical benchmark may then be subject to a regional adjustment (refer to 425.656), a prior savings adjustment (refer to 425.658), or no adjustment (refer to 425.652(a)(8) and (c))

Methods: We searched PubMed, MEDLINE, SCOPUS, and EMBASE databases to identify studies published from 1946 through December 2023, reporting serum values as prognostic factors for BA after HPE, specifically total bilirubin (TB), ALT, GGT, MMP-7, and total bile acids (TBA)