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The examination included collecting anamnesis (including taking urate-lowering drugs (ULD) and colchicine), anthropometric data (height, weight, BMI), determining the level of pain in knee joints using a visual analogue scale (VAS), blood test for UA levels, and performing radiography (TeleCord MT Plus device, Russia) of the knees joints to determine the radiological stage of OA according to Kellgren-Lawrence

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While it may have legitimate therapeutic applications, the cancer-related concerns make me particularly cautious about recommending it, especially in perimenopausal women who already face age-related increases in cancer risk

2.2.1 Enzymatic antioxidants SOD plays a crucial role by converting O 2 - into H 2 O 2 , marking the initial step in the antioxidant process (Powers et al., 2020)