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We hypothesized that it might be possible to separate PTM-containing amino acid pair, l-lactyl lysine and d-lactyl lysine, by HPLC if their difference in stereochemistry could be accentuated by introducing additional chiral chemical group

211 Glycyrrhiza glabra (licorice) is used for dyspepsia and ulcers but can cause pseudoaldosteronism, especially with corticosteroids or diuretics, increasing risks of hypokalemia and hypertension

This may be not only because nicotine is a nicotinic receptor agonist and therefore an opponent of these poisonous metabolites, but nicotine is a strong acetylcholine (ACh) agonist as well 62

TRPV4 may be a potential therapeutic target for DR

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