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Research has found that vitamin B12 provides weight loss to those who increase their intake

If you factor in the bioavailability discount, the effective cost per equivalent systemic dose increases substantially for oral products

doi:10.1007/s10517-014-2343-1

Phase 2 obesity trial doses: 0.6 mg, 2.4 mg, 3.6 mg, and 4.8 mg once weekly

For older adults, especially if their diet is limited, supplemental B12 is usually recommended.[ref] Choosing the right type of vitamin B12 for your genes: Access this content: An active subscription is required to access this content