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The role of protein clearance mechanisms in organismal ageing and age-related diseases

Payne, W

This finding underscores the intricate interplay between iron homeostasis and mitochondrial function and the induction of pyroptotic cell death

Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains

In summary, the use of immune agonists and TME-modulating agents not only amplifies immediate effector responses but also, more importantly, orchestrates the immune system toward the establishment of durable AIM, a paradigm shift essential for overcoming adaptive resistance in cancer immunotherapy