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This patient's normal pulse rate, prominent pulmonary findings, and lack of hypermetabolic symptoms make a thyrotropin-secreting tumor unlikely

e , Control or ZAK KO cells were untreated or treated with UV (20 J/m2, 20 min recovery) and then analyzed as in a

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elegans to reveal potential ancestral functions of PTCH family proteins because it lacks smoothened and other canonical Hh signaling pathway components, which have been lost during evolution 22,23