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In addition, this study will contribute to the literature

50,51,52 IL-6 has the ability to interact with the membrane-bound IL-6 receptor (mIL-6R) present on immune cells, as well as with the soluble form of the IL-6 receptor (sIL-6R), forming a complex that triggers the activation of gp130 and subsequently initiates the JAK/STAT3 signaling pathway