Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) peg6 141 SMILES BrC1=CC=CC2=C1C(=O)C(C1CCC(=O)NC1=O)C2=O Purity (HPLC)
Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) peg6 141 SMILES BrC1=CC=CC2=C1C(=O)C(C1CCC(=O)NC1=O)C2=O Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from established
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