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Mechanism of neurodegeneration PD is caused by the progressive degradation of dopaminergic nerve cells in the substantia nigra, a part of the brain that is essential for controlling movement (31)

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Among all the pathological fibrosis subtypes, the relative area fraction of nodular fibrosis (the fibrosis subtype with patterns consistent with cirrhosis), had the strongest association with the ASH biomarkers (MELD-NA = 0.55