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Before injection (preparation phase) 30 minutes before: Remove tirzepatide from the refrigerator to reach room temperature 15 minutes before: Gather supplies: alcohol swabs, cold pack, hydrocortisone cream, clean needle 1 hour before: Take oral antihistamine (cetirizine 10mg) if you have a history of reactions Choose injection site: Check your log for the last site used

Drinking too much plain water can cause you to lose B12 because it is water-soluble, meaning it is excreted through urine Hydration IV B12 is combined with our Lactated Ringers because the added minerals in LR allow our body to retain fluid, therefore retaining B12

And chances are, someone has suggested trying vitamins particularly vitamin B12 to ease the pain

Science 359 , 11511156 (2018)