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The permeability of mitragynine across the intestinal barrier was also measured using in situ single-pass perfusion technique in rats ( In situ perfusion technique enables measurement of barrier permeability in an intact functional barrier with membrane transporter machinery in place ( P eff was 111 10 6 cm/s

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Concurrent validity analyses demonstrated strong positive correlations for both BBS and TBT with face-to-face results, and moderate negative correlations with MLS, APS, and sway velocity