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Of note, the relative abundance of the Parasutterella genus, which was significantly enriched in both the vehicle- and 5A-1MQ-treated animals transitioned from WD to LD compared to both the WD and LD control groups, was observed to be significantly correlated (either positively or negatively) with 30 EWAT metabolites, both with and without outliers included

This therapeutic effect was observed alongside the suppression of inflammatory and Th1-driven autoimmune response, as well as elevated levels of IL-10 (301)

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4.1.3 Synergistic mechanism of exercise combined with tDCS on cognitive function Combined motor intervention and tDCS can produce synergistic enhancement effects, underscoring the critical influence of brain state during stimulation