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IV infusion therapy may be considered where oral supplementation is: Ineffective due to absorption issues Poorly tolerated Too slow for clinical needs It may be appropriate for patients experiencing: Persistent fatigue Recurrent infections Nutritional deficiencies Post-viral or post-illness recovery Increased physiological stress IV therapy is always used as an adjunct, not a replacement for lifestyle, nutrition, or medical treatment

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However, these conventional anti-TNF- antibodies are somewhat immunogenicity and form resistant antibodies when used (Ishiwatari-Ogata et al., 2022

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