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12 , e1035 (2022)

Science 384 , 1085 (2024)

Psychiatric symptoms are mainly associated with relapse 45,46

At the 200 mcg dose, PYY3-36 failed to reduce body weight, while 60% of patients treated with the high PYY3-36 dose (600 mcg three times a day) dropped out due to nausea and vomiting, so that no meaningful inference could be drawn from the few patients who completed the study on 600 mcg

Graphical Abstract Access this article Similar content being viewed by others Data Availability The data of this study are available from the corresponding author upon request