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The enzyme glutathione reductase (GR) recycles GSSG to GSH with the simultaneous oxidation of -nicotinamide adenine dinucleotide phosphate (-NADPH2)

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There are no data indicating that acetylcysteine influences hepatic failure, but this remains a theoretical possibility

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One double-blind, placebo-controlled trial found a 15% increase in quality of life in elderly, generally healthy people with an ashwagandha root extract, 600 mg per day for 12 weeks, as well as improvements in sleep and mental alertness (see the section: Insomnia/sleep)