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FDA guidance for RUO-labeled in vitro diagnostic products explains that RUO labeling is meant to identify materials in a laboratory research phase and distinguish them from diagnostic contexts [16]

Hepatocyte growth factor induces DNA synthesis and proliferation of vascular endothelial cells through the activation of ERK and STAT3 (Dong et al., 2001

This raises an intriguing question: is the breach of the bloodbrain barrier in AD simply a byproduct of aging, or does it require the presence of these vascular risk factors