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Calcium-independent phospholipase A2 (iPLA2), a member of the PLA2 family, is a cytoplasmic protein with catalytic activity in the absence of calcium, and previous studies have shown that it is associated with metabolic disorders and inflammation [40]

Although some laboratory research progress has been made in ferroptosis as a new target for the treatment of OC, there are still challenges in translating these findings into effective clinical treatments

& Waldbauer, G

In this Perspective, we propose that inhibition of ferroptosis by GPx4 provides protective mechanisms against neurodegeneration

After tipping off the supernatant, diluted supernatants were incubated for 2 hr at RT