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CAR-T cell therapy uses genetic engineering to transform patients T cells into cells capable of specifically identifying tumor cells, thereby enhancing anti-tumor capabilities (137)

However, it is undeniable that macrophages play an important role in the inflammatory response experienced by the intestine after HS [12], so promoting the polarization of M2 macrophages may be a new therapeutic strategy to control intestinal inflammation

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doi: 10.1016/S0049-3848(16)30095-0