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Reduces premature ageing

10.1111/j.1749-6632.1983.tb47276.x

In the sections that follow, we build on this conceptual framework to examine how major proteostasis machineries contribute to cellular and organ-level resilience and how their failure drives pathology across cardiovascular, cancer, metabolic, neurodegenerative and autoimmune disorders and highlight therapeutic strategies aimed at reinforcing proteostasis resilience

From a clinical perspective, patients can be divided into different subgroups on the basis of differences in glutamine metabolism across different cancer types, which has important application prospects in cancer prevention, screening, and treatment

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