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Despite having distinct clinical presentations, both conditions are characterized by intricate inflammatory processes (Figure 2)

This creates a supportive network that maintains cellular balance

10.1074/jbc.275.15.11181 36 DangC

Modulation of Pathological Protein Aggregation Curcumin exerts neuroprotective effects, in part, by modulating the aggregation of key pathological proteins implicated in neurodegenerative disorders, including amyloid- (A) in Alzheimers disease, -synuclein in Parkinsons disease, and Tau in tauopathies

Moreover, subtype-specific expression of transcription factors (TFs) has been demonstrated: MAFA and SIX2/3 in -cells, IRX2 in -cells, NKX6-3 in -cells, MEIS2 in -cells, and AFF3 in -cells