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Demjaha A, Egerton A, Murray RM, Kapur S, Howes OD, Stone JM, et al

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We had concerns that our IP daily dosing delivery strategy may not have allowed for sustained inhibition of CK1/-mediated phosphorylation for TDP-43 throughout the day, so we conducted an additional efficacy study using special diet chow formulated with CK1/-specific PF-05236216 inhibitor for continuous delivery of inhibitor

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