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One US analyzer study found that automated and manual nucleated red cell counts correlated at a Pearson r of 0.97, a very strong agreement, per the American Journal of Clinical Pathology

While there are several methodological limitations to these studies, they suggest that there is not a major difference in cost between the IV and oral route

Moreover, in an effort to recapitulate an AS-like state in WT NPCs, we supplemented the WT NPCs cell culture with BSO, a potent inhibitor of glutathione synthesis, which reduced the glutathione levels by ~50% (Fig