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In addition, ABCG2 rs2231142 considered a risk allele for gout ( PDZK1 Polyvalent PDZ domain 1 (PDZK1) is a multi-domain protein containing four PDZ domain tubular cells observed in the apical membrane of the kidney proximal tubule

This upregulation leads to an increased expression of lipogenic genes, including sterol regulatory element-binding proteins (SREBP1c) and diacylglycerol acyltransferase-2 (DGAT2), which suggests that miR-370 provides a further point of regulation of this pathway 86

Additionally, NCOA4-ferritin heavy polypeptide 1-mediated iron metabolism disorder is related to retinal ganglion cell ferroptosis following pathologically high intraocular pressure injury [37]

Supportive role of probiotic strains in protecting rats from ovariectomy-induced cortical bone loss

10.1038/s41574-022-00794-0 Nat