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These findings confirm those of an earlier pilot study by the same researchers with the exception that cystathione was found to be lower in children with autistic disorder in the pilot study [46], as well as a later study by the same research group which focussed on a subgroup of children with autistic disorder who had abnormal methylation and/or GSH:GSSG [48]

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3.2 Mechanism of NLRP3 inflammasome activation Currently, NLRP3 inflammasome activation pathways are broadly categorized into canonical, noncanonical, and alternative pathways (Figure 1), with classification criteria predicated on stimulus specificity (e.g., PAMP vs

Low glutathione also expresses itself in signs of aging, such as wrinkles and loss of elasticity in the skin