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Lipid nanoparticles strategies to modify pharmacokinetics of central nervous system targeting drugs: crossing or circumventing the blood-brain barrier (BBB) to manage neurological disorders

doi: 10.1002/jimd.12092

In view of low prevalence of TPMT polymorphism in Indian and Asian populations, high cost and unavailability of the test, and absence of clear correlation between the polymorphism and azathioprine intolerance, TPMT testing is not routinely recommended in Indian children [78]

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