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The primary victims of this relentless oxidative stress are the mitochondria, the microscopic powerhouses responsible for generating ATP

Thus, dissecting the contributions of E1, E2, and E3 components in cardiomyocytes is fundamental to understanding how UPS perturbations drive cardiovascular diseases

Theat least partial [24,97]structural and chemical similarity to physiological bio-molecules can explain the ability of thiol-bound Mercury(II) species to cross biological membranes by using the physiological transport systems of the natural substrates [21] and its ability to undergo chemical modifications operated by the enzymes which process bio-molecules such as those of the soluble thiolome

Rheumatology 54 (2), 363368

10.3390/nu13093238 Nutrients