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A lower than normal WBC count may be due to: Bone marrow deficiency or failure (for example, due to infection, tumor, or abnormal scarring) Cancer treating drugs, or other medicines (see list below) Certain autoimmune disorders such as lupus (SLE) Disease of the liver or spleen Radiation treatment for cancer Certain viral illnesses, such as mononucleosis (mono) Cancers that damage the bone marrow Very severe bacterial infections Severe emotional or physical stress (such as from an injury or surgery) An ethnic/genetic trait (not uncommon in African Americans) HIGH WBC COUNT A higher than normal WBC count is called leukocytosis

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According to the Response Evaluation Criteria in Solid Tumors 1.1 [15], tumor lesions were assessed at baseline, every two cycles until 6 months, and then every 24 cycles after 6 months until PD

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See the concern with NAC connecting to glutathione for more information on this complex metabolic process.