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By month fifteen, the trial's primary endpoint, the average participant had lost 15.2 percent of their starting weight, and the curve had become essentially horizontal [Garvey et al., Nature Medicine, 2022]

Yang J, Tong Q, Zhang Y, Yuan S, Gao Y, Deng K, Wang Y, Lu J, Xie X, Zhang Z (2021) Overexpression of nicotinamide N -methyltransferase mainly covers stroma of colorectal cancer and correlates with unfavorable survival by its product 1-MNA

Weeks 46 : first measurable waist or body-fat changes in responders, based on research community reports

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[DOI] [PubMed] [Google Scholar] 86.Dawkins MJ, Scopes JW