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The expression of GPX3 was positively associated with plasma cells and M0 macrophages, whereas it exhibited a negative association with monocytes and M1 and M2 macrophages

22 The gut microbiota also impacts bile acid metabolism and composition through enzymatic actions like bile salt hydrolase (BSH)

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For instance, through blocking the System Xc activity, erastin triggers ferroptosis, eventually inhibiting tumor growth in mouse models of lymphoma (114)

Glutathione is the major detoxification molecule found in every cell of the body