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Name: glutathione scavenger in swedish Oxidants and Antioxidants Selenium and selenoproteins: key regulators
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Furthermore, they influence melanoma cells by inhibiting the prosurvival protein Akt and inducing hypophosphorylation of the retinoblastoma protein (pRb), thus disrupting the cell cycle and triggering apoptosis-mediated cell death (Velasco et al., 2016)

A variety of STING agonists are currently in clinical trials, most of which focus on the anti-tumor effects of combinations of STING agonists with ICIs (Table 1)