glutathione peroxidase video 2 - an overview Concerted action of Glutathione peroxidase-1,

As treatments impose selective pressures, sensitive clones are eliminated, while resistant clones survive and proliferate

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PMID 11457926

GR is another critical enzyme involved in antioxidant defense and responsible for reducing GSSG back to its reduced form GSH, which is pivotal for the cellular antioxidant protection 53

It is important to consider the possibility that cancer cells may develop resistance to cholesterol-lowering drugs