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This challenging disease characterized by persistent airway inflammation cannot be cured

Cytochrome P450 Oxidoreductase Contributes to Phospholipid Peroxidation in Ferroptosis

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The most common adverse reactions (all Grades) reported in at least 5% of participants receiving YEZTUGO in either PURPOSE 1 or PURPOSE 2 were injection site reactions, headache, and nausea

Researchers planning protocols are referred to the original primary literature cited in the References section for full methodological detail, including vehicle composition (the Sun 2021 vehicle was 10% DMSO, 40% PEG300, 5% Tween-80, 45% saline), administration timing relative to behavioral testing, and outcome assessment timepoints