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While certain tumor cells, like MDA-MB-231 cells, display positive durotaxis by moving from soft (0.5 kPa), to stiff (22 kPa) substrates [95, 96], others, such as U-251MG glioblastoma brain tumor cells, undergo negative durotaxis, migrating from 22 kPa regions towards softer, 10 kPa, areas [96]

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Hypertrophic and keloid acne scars form when the skin overproduces collagen during wound healing, creating firm, elevated tissue above the surface

CPT codes 95250 and 95251 may not be reported more than once per month per AMA CPT guidelines