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FIGURE 4 GSTP1 Activity in GSH-Conjugation of AQ-QI and DEAQ-QI To investigate the intracellular GSTP1-mediated GSH-conjugation of AQ-QI or DEAQ-QI, AQ-SG, and DEAQ-SG formation were measured in total lysates directly after QI exposure

The findings highlight a strong connection between the gut-brain axis, chronic stress, mental health disorders, and CKD, indicating that addressing mental health and gut microbiota changes may be important for managing CKD progression