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Bone structure and natural healing process Hierarchical organization: Bone consists of mineral phase (hydroxyapatite calcium phosphate crystals providing hardness), organic phase (type I collagen fibers providing flexibility), and cellular components (osteoblasts building bone, osteoclasts resorbing bone, osteocytes sensing mechanical stress)

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Presenilin is essential for ApoE secretion, a novel role of Presenilin involved in Alzheimer's disease pathogenesis

It may also encourage healthy nitric oxide levels in the arteries, which can support endothelial function and arterial blood flow and has been shown to promote a healthy inflammatory response and platelet function

10.1016/0926-6917(95)90040-3 81 GoedertM