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IFN-I-mediated neutropoiesis bias drives neutrophil priming and inflammatory comorbidities

10.3389/fphar.2024.1393209 171 XiaJ.LvL.LiuB.WangS.ZhangS.WuZ.et al

This article aims to provide a comprehensive review on the application of phytomedicines in preventing and treating the APDs-induced EPS or EPS-like behaviors by summarizing their therapeutic effects and outlining the underlying neurobiological mechanisms

PAR3 downregulation in HER2 + BC activates RAC1 (Ras-related C3 botulinum toxin substrate 1), reducing E-cadherin stability, loosening intercellular junctions, and promoting metastasis [71]