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thus, it can induce the demethylation of DNA and histone H3K27m3 in the promoter region of genes involved in neurogenesis and differentiation, an effect mediated by Tet1 and Jmjd3 demethylases, respectively

"Alpha lipoic acid for symptomatic peripheral neuropathy in patients with diabetes: a meta-analysis of randomized controlled trials." Int J Endocrinol

Many people with polycystic ovary syndrome (PCOS) also have insulin resistance

First, Sensing and Destruction: COFs, equipped with precisely integrated sensitizing units, efficiently respond to external stimuli (e.g., light, ultrasound, radiation) or endogenous triggers (e.g., H 2 O 2 ), generating intense local biochemical effects such as bursts of ROS, hyperthermia, or DNA damage ( Figure 2 ) (155, 156, 166)

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