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Furthermore, SBT system-derived ICC was identified by the expressions of HA, Myc, CK19 (a biomarker of BECs and ICC), and Ki67 (a biomarker for proliferation) (Fig

We used 18-month-old mice for organoid isolation and NanoSeq sequencing of wild-type and Polk-/- mice, and 7-month-old mice for cholangiocyte organoid isolation of Xpa-/-Polk-/-, Xpc-/-Polk-/- and age-matched controls

Hepatology 47 , 544551 (2008)

The earliest changes occurred in a highly correlated cluster of CognitionOrganismal proteins: pleiotrophin (PTN), transgelin (TAGLN), WNT1 Inducible Signalling Pathway Protein 2 (WISP2), CUB Domain Containing Protein 1 (CDCP1) and chordin like 1 (CHRDL1